A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a method to visualize different types of chromatin and reveal their distinct ...

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility. Using the ...

Live-cell fluorescence imaging has revolutionized how protein localization and dynamics are studied. Proteins execute their functions by interacting with a complex network of biomolecules. However, ...

Targeting cells for ablation, gene therapy or drug delivery is an ongoing challenge in development of therapeutics. With the goal of efficiently labeling cell surfaces based on target recognition, we ...

Scientists in Tokyo have developed a groundbreaking, label-free method to identify aging human cells using electric fields. This new technique avoids the downsides of chemical tagging, which can ...

A mouse brain hemisphere stained with various cell type makers: neurons overall (cyan), and cells specifically involved with neurotransmitters dopamine (yellow) and acetylcholine (magenta). A new ...

Movie 1: Movement of single nucleosomes in living human cells. The movie shows nucleosome fluctuations in euchromatin (left), where gene expression is active, and in heterochromatin (right), where ...

Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single cells. A ...

Profiling the proteins that cells are making is a staple of studies in biology, neuroscience and related fields because the proteins a cell is expressing at a given moment can reflect the functions ...