In vitro assay evaluation is a critical component for T cell engager (TCE) drug discovery, providing essential insights into ...

Optimizing the formulation of reagents for your qPCR assay requires careful experimental design that looks across several performance factors for each reagent formulation tested. These performance ...

Fragile X Syndrome (FXS) is caused by a trinucleotide expansion leading to silencing of the FMR1 gene and lack of expression of Fragile X Protein (FXP, formerly known as Fragile X Mental Retardation ...

When working in a lab, launching a quantitative PCR (qPCR) experiment demands a comprehensive understanding of complicated protocols, principles, and methodologies. Analyzing the large amounts of ...

The combined software package enables seamless access of the latest crude assay information throughout plant lifecycle modeling, from design through operations and performance optimization. Invensys ...

The clonogenic assay measures the capacity of single cells to form colonies in vitro. It is widely used to identify and quantify self-renewing mammalian cells derived from in vitro cultures as well as ...

(A) Comparison of measured values for quality control materials at the 10% level before and after optimization. A-1 to B-2 represent individual participating laboratories; (B) Comparison of measured ...

Approved biological products are required to be accompanied by analytical tests to demonstrate safety, purity, and potency. Manufacturing and testing processes for approved products are validated and ...

Advanced Strategies to Study Plasma Protein Binding, Improve PK/PD, and Develop Better Enzyme Inhibitors In early drug discovery, the molecular hits generated from a high throughput screen (HTS) are ...

HTS is an automated experimental approach used to rapidly evaluate thousands to millions of samples—such as chemical compounds or genetic perturbations—against a defined biological target or pathway.

VolitionRx Limited (VNRX) has entered into a strategic collaboration agreement with global in vitro diagnostics leader Sysmex ...

This article and associated images are based on a poster originally authored by Tika R. Malla, Emma Mead and Emma J. Murphy and presented at ELRIG Drug Discovery 2024 in affiliation with University of ...