Bayern Munich hope to turn their first leg advantage into a spot in the UEFA Champions League quarterfinals on Tuesday, taking on Bayer Leverkusen in a matchup between the last two Bundesliga winners.

Leverkusen, the defending German champion, which had never lost to Bayern in six matches under Alonso, capitulated with a 0-3 loss to Bayern last week.

Bundesliga leaders Bayern Munich have been stunned by lowly Bochum in a 3-2 home defeat on Saturday, while champions Bayer Leverkusen also suffered a shock 2-0 loss on their home turf to Werder Bremen. Bayern found themselves down to 10 men as they suffered their first league defeat in 2025 on Saturday.

Champions League betting tips for Bayern Munich v Bayer Leverkusen as Kevin Hatchard picks out two odds-against.picks including Nathan Tella shots at the Allianz Arena

Six-time Champions League winners Bayern Munich hosts reigning Bundesliga champions Bayer Leverkusen in the first leg of their UEFA Champions League Round of 16 tie on Wednesday evening at the iconic Allianz Arena.

Since Xabi Alonso took the helm at Bayer Leverkusen in late 2022, he has been a major thorn in his former side Bayern Munich.

Xabi Alonso followed up his first loss to Bayern Munich as Bayer Leverkusen manager with his second just a week later, as his team crashed out of the Champions League. Following the second leg 2-0 loss,

Confirmed starting XI for Champions League Round of 16 first-leg clash between Bayern Munich and Bayer Leverkusen.