Nature

Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues

Genetic association mapping produces statistical links between phenotypes and genomic regions, but identifying causal variants remains difficult. Whole-genome sequencing (WGS) can help by providing ...
Nature

Triangulation for causal loop diagrams: constructing biopsychosocial models using group model building, literature review, and causal discovery

This paper provides an empirical case example of a mixed methods triangulation approach to CLD development. The case example seeks to map the biopsychosocial feedback mechanisms underlying the course ...