The approval was supported by a systematic review of published literature that included 46 patients with FOLR1-CFTD treated with leucovorin through various administration routes. The Food and Drug ...

A medication used primarily to help relieve the side effects of chemotherapy has been given the green light to be used as a treatment for a rare neurological disorder. However, the FDA announcement ...

Frye believes that cerebral folate deficiency is present in many children with autism. But confirming the deficiency requires a spinal tap, which can be painful. As a result, Frye says, he and other ...

Robert F. Kennedy Jr., the United States Secretary of Health and Human Services, earlier claimed that the drug leucovorin could help treat autism. However, two officials from the U.S. Food and Drug ...

Corrections and clarifications: Due to an editing error, a previous version of this story mischaracterized the scope of the new FDA approval for leucovorin. The Food and Drug Administration has denied ...

Six months ago, the federal government loudly proclaimed the likely benefits of an existing drug called leucovorin for treating autism. Now that proclamation has officially turned into a whimper. On ...

Severe cerebral folate deficiency can present in infancy as irritability, sleep disturbance, and difficulty with muscle coordination and development. Some babies even have smaller heads than usual and ...

At a press conference in late 2025, federal officials made some big claims about leucovorin, a prescription drug usually reserved for people on cancer chemotherapy. "We're going to change the label to ...