It should be noted that off-target binding of the drug could lead to ADRs and may not be related to the same level of exposure that is responsible for on-target efficacy. Thus, an understanding of ...

Researchers have identified an increasing trend in medicine-related harm leading to hospital admission. Researchers at the University of Liverpool have identified an increasing trend in ...

Adverse drug reactions (ADRs) remain a common clinical problem since they can mimic many diseases and cause significant morbidity and mortality. Judicious prescribing is important to minimize their ...

Please provide your email address to receive an email when new articles are posted on . During 4.7 years, 360 patients had 488 serious adverse reactions. More than 27% of serious reactions were ...

Slower metabolism, compromised adherence, and potential interactions present new challenges as patients get older. Here’s how to manage them. Tom was 90. A retired businessman, he was still happily ...

Of more than 100,000 suspected adverse drug reaction reports registered in EudraVigilance, most related to C difficile were associated with ciprofloxacin, ceftriaxone ...

Multimorbidity is common in patients with chronic obstructive pulmonary disease (COPD), and is associated with high levels of polypharmacy, which can lead to an increased risk of adverse drug ...

Laura A. B. Wilson receives funding from the Australian Research Council. Shinichi Nakagawa receives funding from the Australian Research Council. Compared to men, we know much less about how women ...

Credit: Getty Images Cautious drug prescription and frequent drug monitoring are needed in patients with CKD, especially as kidney function declines, according to investigators. Given the elevated ...

Adverse drug events are more common in older people with comorbidities, a new study finds. Factors that are independently linked with adverse drug events are being female, taking more drugs daily, ...