Biologists studying human reproduction have identified what is likely the major contributing factor to the maternal age-associated increase in aneuploidy, the term for an abnormal number of ...
Figure 1: Hsk1–Dfp1 interacts with and phosphorylates Swi6. Figure 2: S-phase activity of Hsk1–Dfp1 is required for equal chromosome segregation. The activity of Hsk1–Dfp1 on Swi6 after its initial ...
Chromosome segregation consists of a series of highly orchestrated events that are essential for cell division. A central aspect of this process is cleavage of cohesin, a multisubunit complex that ...