It is vital to the regulation of cell activities through its role as a second messenger. Calcium signaling is the process whereby low cytoplasmic concentrations are deliberately increased to activate ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

"Having this pathway modeled is a valuable research tool because there is a strong link between abnormalities of calcium handling and cardiac arrhythmias. In addition, being a first mathematical model ...