The gold standard of quality assessment of drugs is nowadays an HPLC using a reversed-phase (RP) column chromatography and aqueous buffers, acetonitrile, and/or methanol as mobile phase, com ...
The use of acidic MPAs (pH 2–4) is the default in pharmaceutical testing because they suppress silanol ionization (from Si-OH to Si-O -) and improve peak shape for basic drugs. However, highly ...
High-performance liquid chromatography is supposed to be complicated, right? Imagine trying to find the correct mobile phase, stationary phase, column length, diameter, particle size, solvent strength ...
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