Human iPSC-derived models currently used in eye research usually replicate later events of tissue differentiation rather than early steps involving concurrent development of diverse embryonic cell ...

Apple snails can fully regrow their eyes, and their genes and eye structures are strikingly similar to humans. Scientists mapped the regeneration process and used CRISPR to identify genes, including ...

The generation of a self-formed, ectodermal, autonomous multi-zone (SEAM) relies on intrinsic developmental processes to guide the differentiation and self-organisation of human induced pluripotent ...

A snail may hold the key to restoring vision for people with some eye diseases. Golden apple snails (Pomacea canaliculata) are freshwater snails from South America. Alice Accorsi became familiar with ...

Paired box 6 (PAX6) is a member of the highly conserved paired box (PAX) transcription factors. Transcription factors regulate the activity of large numbers of genes involved in development. The PAX6 ...