DNA gyrase, a bacterial type II topoisomerase, is instrumental in maintaining DNA supercoiling during replication and transcription. Owing to its absence in higher eukaryotes, it represents an ...
Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.
Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified ...
These two images demonstrate synthetic lethality with a non-responsive cell line (right) compared to a responder to ATR ...
A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center ...
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Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer
A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer ...
Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...
Funding to support Phase 1 clinical development of best-in-class PARG inhibitor candidate FORX-428FORX-428 is potential new ...
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