Cells require lipids to maintain their integrity and separate cellular functions for appropriate homeostasis and regulation. Advances in lipid detection methods and techniques to probe lipid functions ...

Lipid molecules form the membranes that organize cellular biochemistry in all domains of life. Imaging approaches have been developed to visualize different types of lipid at subcellular scales and ...

The body has to clear away dead cells and other unnecessary or unneeded stuff, and one mechanism that is crucial to the degradation of such materials is called LC3-associated phagocytosis (LAP). This ...

In aging and many diseases, muscles degenerate and there is a loss of function that can lead to many other health problems. As skeletal muscles break down, people can become frail and experience a ...

A new microfluidic method preserves worm anatomy to link lipid signals with body structure using mass spectrometry imaging. Understanding how fat molecules are distributed and function in living ...

A noticeable deficit of highly unsaturated lipids — including omega-3 fatty acids — found in women with Alzheimer's disease (AD) but not in cognitively healthy women is linked to worse cognition and ...

Women with Alzheimer's had lower levels of unsaturated lipids, including omega fatty acids, compared with cognitively healthy women. This difference was seen in women but not men, suggesting ...

From vaccine development to cancer and cell or gene therapies, LipidLaunch™ research-ready lipid nanoparticles and reagent ...

Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway. Researchers now ...