Androgens exert their effects largely by binding to nuclear androgen receptors to regulate gene expression, but they can also bind to receptors in plasma membranes to rapidly induce cellular responses ...

Some products of arachidonic acid have already been well studied: the prostanoids formed by cyclooxygenases are central ...

About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane ...

A groundbreaking study reveals how neurons sense and transmit mechanical forces across their membranes—a key to understanding touch, movement, and development.

New study shows that targeting an oft-drugged family of cell membrane receptors with biased modulators can expand potential ...

How do embryos develop? Why does the cortex of the mammalian brain fold? How do we feel touch at our fingertips? These and ...

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, ...

Study sets stage for development of synthetic biosensors with custom-built sensing and responses for basic and translational cell engineering applications.