Recently identified and long-lasting type of protein misfolding — non-native entanglements — observed in all-atom protein folding simulations. Representative misfolded conformations of the small ...

AlphaFold didn't accelerate biology by running faster experiments. It changed the engineering assumptions behind protein ...

Protein hydrophobicity is a fundamental driver of protein folding dynamics, underpinning the formation of a central hydrophobic core that stabilises the three-dimensional structure amid an aqueous ...

VERONA, Italy--(BUSINESS WIRE)--Sibylla Biotech today announced the successful close of its €23 million Series A financing round to fund the further development of its Pharmacological Protein ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin introduces a breakthrough in protein simulation. The study, published in the ...

CGSchNet, a fast machine-learned model, simulates proteins with high accuracy, enabling drug discovery and protein engineering for cancer treatment. Operating significantly faster than traditional all ...

MILAN--(BUSINESS WIRE)--Sibylla Biotech announced today a drug discovery collaboration with Ono Pharmaceutical Co., Ltd. (TSE: 4528) that will access Sibylla’s cutting-edge Pharmacological Protein ...

Stanford University’s Folding@Home project, which puts personal computers to work studying the complicated process of protein folding, could soon get a big boost from an unlikely direction. Starting ...

HOUSTON and MILAN ― The University of Texas MD Anderson Cancer Center and Sibylla Biotech today announced a strategic collaboration agreement to discover and develop novel small-molecule cancer ...

Overview of the PSP pipeline. Following genomic sequencing, the primary amino acid sequence is determined. The experimental method then starts with expressing this protein by genetically modifying ...