Herpes simplex virus type 1 (HSV-1) infection dramatically remodels the host cell's nuclear structures. Infection leads to ...

A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible for ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, ...

The innate immune system is the body's first line of defence against pathogens like bacteria or viruses. TRIM25 is a protein that is important in the innate immune response against RNA viruses, such ...

Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University of Connecticut researchers have shown that packaging mRNA like a virus could ...

Nipah virus was first identified in 1998 during an outbreak among pig farmers in Malaysia. Later, pteropus bat populations have been identified as its primary reservoir. How do factors like ecological ...

For decades, biology textbooks have drawn a firm line: viruses are not alive. They lack the machinery to reproduce on their own, they carry no metabolism, and they depend entirely on host cells to ...

Mammalian immunity has long been thought to rely solely on proteins and specialized immune cells. However, a newly proposed concept—RNA immunity—is reshaping this perspective. In a recent publication ...

Using genomics, evolutionary biologists test several hypotheses on the origin of viruses. New evidence suggests they may have emerged more times than previously thought. Corroborating the virus-first ...