New research from the University of Minnesota Medical School has identified fatty acids that selectively induce death in senescent cells—the culprits behind aging and many chronic diseases—opening new ...

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation ...

Aging is the progressive loss of tissue and organ function over time 1. The antagonistic pleiotropy theory of aging proposes that organismal fitness declines, at least in part, because natural ...

UConn Health scientists have discovered that eliminating old, dysfunctional—senescent—cells in human fat can alleviate characteristic signs of diabetes. Their studies showed that using two ...

Tumor suppressing senescent cells are bad for aging. The no-longer-dividing cells release a continual cascade of inflammatory factors and are implicated in many maladies including arthritis, ...

Stem cells are totipotent and can remain dormant or become active to regenerate cells of a specific tissue. Either of these actions is the result of niche signals. In melanocytes, such niche signals ...

Illustration of CAR (chimeric antigen receptor) T cell immunotherapy, a process that is being developed to treat cancer. T cells (blue), part of the body's immune system, are taken from the patient ...

EVER wanted to be immortal? Be careful what you wish for. Living forever wouldn’t just mean outliving your friends, family and descendants, there’s also the inconvenient reality of ageing. Beyond the ...