Researchers show amyloid beta and tau compete for microtubule binding, disrupting cellular transport. This interference may ...

In Alzheimer's Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons ...

The traditional view of tau is that of a rather dull microtubule-binding protein that occasionally goes rogue, wandering off into other cellular compartments where it stokes neurodegeneration. At ...

Clumps and tangles of tau protein are associated with Alzheimer's disease and other dementias, but tau protein also plays a role in healthy nerve cells. Healthy tau can assemble into an envelope ...

Tau proteins act like the brain's maintenance crew, helping maintain the structure and proper function of brain cells. In neurodegenerative diseases such as Alzheimer's, the tau proteins can form ...

Please provide your email address to receive an email when new articles are posted on . Large amounts of tau proteins in the brain affected memory function only when amyloid protein burden was also ...

Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the “tau interactome” uncovering new findings about the role of tau in neurodegenerative disease.

The research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University published a research article entitled "Quantitative Chemoproteomics Reveals ...

In Alzheimer's Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons ...