Before making any MLB picks or building any MLB parlay cards, you'll want to see the MLB predictions and betting advice from SportsLine's proven computer simulation model. You can also check out our best Saturday MLB prop bets and our top home run picks for Saturday.

The Red Sox opened favorites to win the primetime game on Fox that features the Yankees starting southpaw Ryan Yarbrough, but it’s a pick’em at BetMGM as of early Saturday afternoon. Crochet has been utterly dominant for the Red Sox in one of their few bright spots during a disappointing season.

Big day of baseball, and our expert MLB predictions have prop betting options for Pete Alonso, Jacob deGrom, and Vinnie Pasquantino!