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Abstract Risk prediction models are an important part of assessing operative mortality and postoperative complication rates in current cardiac surgery practice. Furthermore, they guide clinical ...

Mouse double minute 2 (MDM2) is an oncogenic E3 ligase that effectively degrades the tumor suppressor p53. In the past two decades, many MDM2 inhibitors that disrupt MDM2-p53 binding have been ...

Student evaluations of teaching (SET) are widely used in academic personnel decisions as a measure of teaching effectiveness. We show: SET are biased against female instructors by an amount that is ...

Postural tachycardia syndrome (POTS) is a chronic autonomic disorder characterized by excessive heart rate elevation upon standing or head-up tilt, in the absence of orthostatic hypotension. This ...

Prostate cancer (PCa) screening with PSA (prostate-specific antigen) remains controversial. PSA is specific to the organ but not to cancer, and different benign conditions can influence the value, ...

This issue is about labour organisation, working class struggles and popular protests. 1 It is about the ambivalent role that trade unions play in the organisation of workers and labour struggles as ...

Background: Age-related vulnerable characteristics of pancoronary plaques in patients with ST-segment elevation myocardial infarction (STEMI) have not been systemically evaluated by optical coherence ...

War is the most destructive of human actions, leaving a legacy of hatred, violence, and destruction which can often take decades to rebuild. The victims of war are endless, from those directly ...

A multi-country cholera outbreak has occurred in several developing countries in Africa, Asia and Oceania since mid-2021. The current multi-country cholera outbreak has spread primarily in Africa. As ...

Phosphodiesterase-4 (PDE4), a member of the phosphodiesterase superfamily, has highly important roles in cyclic nucleotide signaling pathways and a variety of skin disorders. Blocking PDE4 activity ...

COVID-19, a disease caused by SARS-CoV-2 that produces major symptoms of pneumonia, has been a disaster worldwide. The traceability of SARS-CoV-2 and the discovery of susceptible animal species is ...