Gut

Macropinocytosis of neutrophil extracellular trap by gastric cancer cells promotes immune escape and peritoneal metastasis

Background Patients with gastric cancer (GC) and peritoneal metastasis (PM) have poor prognoses due to drug resistance and ...
Gut

Impact of initial severity and progression pattern of new-onset diabetes on pancreatic cancer risk: a 15-year longitudinal nationwide cohort study

Background New-onset diabetes (NOD) increases the risk of pancreatic cancer. Previous studies have mainly focused on the ...
Gut

Faecal proteases and immune signatures drive subtype-specific enteric neuronal activation in IBS

Background Luminal proteases have been implicated in epithelial barrier dysfunction and visceral hypersensitivity in ...
gut.bmj

P176 Effects of subcutaneous guselkumab induction and maintenance on histologic outcomes in moderate-to-severe crohn’s disease in the phase 3 GRAVITI study

Introduction Guselkumab (GUS) is a dual-acting IL-23p19 subunit inhibitor that was efficacious in double-blind, placebo-controlled, treat-through trials in participants (pts) with moderately to ...
gut.bmj

The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers

Department of Medicine, University Hospital of South Manchester, Manchester M20 2LR, UK Correspondence to: Dr L A Houghton, Department of Medicine, University Hospital of South Manchester, Nell Lane, ...
gut.bmj

Acute severe ulcerative colitis trials: the past, the present and the future

Correspondence to Dr Laurent Peyrin-Biroulet, Department of Gastroenterology, INFINY Institute, Nancy University Hospital Center, Vandœuvre-lès-Nancy, Grand Est, France; peyrinbiroulet{at}gmail.com ...
gut.bmj

A simple clinical colitis activity index

a Inflammatory Bowel Disease Study Group, Royal Free Hospital School of Medicine, London, UK, b Gastroenterology Unit, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK Dr R N Allan, Queen Elizabeth ...
gut.bmj

YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
gut.bmj

Dietary fibres and IBS: translating functional characteristics to clinical value in the era of personalised medicine

Clinical guidelines in the use of fibre supplementation for patients with IBS provide one-size-fits-all advice, which has limited value. This narrative review addresses data and concepts around the ...
gut.bmj

Bile reflux gastritis and Barrett's oesophagus: further evidence of a role for duodenogastro-oesophageal reflux?

a Academic Unit of Pathology, University of Leeds, Leeds, UK, b Centre for Digestive Diseases, General Infirmary at Leeds, Leeds, UK Professor M F Dixon, Academic Unit of Pathology, Algernon Firth ...
gut.bmj

Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study

Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan Dr H Isomoto, Second Department of Internal Medicine, Nagasaki University School of Medicine, 1-7-1 ...
gut.bmj

The early prediction of mortality in acute pancreatitis: a large population-based study

Background: Identification of patients at risk for mortality early in the course of acute pancreatitis (AP) is an important step in improving outcome. Methods: Using Classification and Regression Tree ...