DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
A new study shows how histones undergo correct chemical modifications during synthesis to guide new therapies.
Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in ...
CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
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New insights into how a molecular gatekeeper controls early protein modification
For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have ...
No treatment-related adverse toxicity was observed across completed GLP studies, with consistent systemic exposure following ...
Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...
At the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, mouse geneticist Antoine Peters and his team investigate how ...
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