A single-vehicle crash has caused a lane closure on Interstate 65 in Lowndes County, according to the Alabama Law Enforcement Agency.

The southbound lanes of Interstate 65 in Butler County are closed while first responders are on the scene of a multi-vehicle crash.

The crash happened just before 9 p.m. at mile marker 72. This story is developing. Stay up-to-date with WSMV4.

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