FDA approval establishes the first newly approved mRNA platform vaccine for seasonal influenza, indicated in adults ≥50 years for prevention of influenza A subtypes and influenza B. Evidence in ages ...

Behind sparsentan's approval sits a trial built on stringent inclusion criteria and evolving endpoint science, raising hard questions about which real-world FSGS patients the data actually represents.

A matched cohort analysis of CPRD Aurum (46 million records) compared 2.45 million AD-exposed versus 11.64 million unexposed individuals, identifying 329,821 herpes zoster events. Adjusted estimates ...

National Medicaid expansion work requirements start in 2027 and hinge on 80 hours of qualifying activity monthly, reframed as “community engagement,” with broad implications for ~20 million ...

Projections estimate 45% of diabetes-related Medicaid coverage losses will stem from state provider tax changes, with additional attrition from eligibility redeterminations, community engagement ...

The Inflation Reduction Act’s Medicare drug price negotiation program may provide disincentives for the development of biosimilar development, James D. Chambers, Ph.D., a profes ...

Journavx revenue rose 71% QoQ and >4× YoY, supported by rapidly expanding utilization across hospital and retail channels, reaching nearly 900,000 prescriptions in 1H2026. Payer coverage broadened ...

ALK rearrangements occur in approximately 4% to 5% of NSCLC cases, and successive ALK TKIs have transformed prognosis, making first-line targeted therapy standard over chemotherapy in metastatic ...

Melody Chang, RPh, BCOP, MBA, of the American Oncology Network, discusses building outpatient infrastructure for bispecific antibody and CAR-T therapy. American Oncology Network (AON) has administered ...

Efficiency frontier analysis defines “nondominated” therapies by incremental clinical benefit relative to drug cost, avoiding QALY-based valuation while still enabling comparative cost-efficiency ...

Repurposing formoterol for MASH is supported by preclinical efficacy, initially observed incidentally during diabetic kidney injury experiments showing reduced hepatic fat in treated mice. High-fat ...