Here are the top betting storylines going into Week 18 of the NFL season, with all odds from BetMGM: How weird is the NFC South? The Buccaneers have lost seven of eight games and are still favored to beat the team in first place of the division. Tampa Bay is a 2.5-point favorite over the Panthers.

Week 18 can bring a wide variety of games, from must-win scenarios (Carolina Panthers at Tampa Bay Buccaneers and Baltimore Ravens at Pittsburgh Steelers) to games key for playoff seeding to games that will only impact the draft order.

The NFL's Week 18 schedule is about to fall into place, but there's still some sorting out to be done in the penultimate week of the regular season.

Well, folks, it is finally here: the last week of the 2025 NFL regular season. There are still top seeds and a couple of playoff spots to sort out, and the action will be hot and heavy this coming week.