Enlicitide decanoate demonstrated meaningful LDL lowering in patients with heterozygous familial hypercholesterolemia and ...

When the amount of cholesterol in the blood is too high, hypercholesterolemia can develop, causing serious damage to the ...

Merck & Co.’s ambition to get the first oral PCSK9 inhibitor to market came one step closer this morning as the pharma ...

Topline data were announced from two phase 3 trials evaluating enlicitide decanoate for the treatment of adults with hyperlipidemia.

A study showed that hospitals bought by private equity firms were admitting disproportionately healthier patients with heart ...

A new method, based on the use of molecules known as polypurine hairpins, facilitates the uptake of cholesterol by cells and ...

Enlicitide, which could be the first oral medication that blocks the protein PCSK9, helped cut cholesterol levels in a pair ...

Currently available PCSK9-targeting therapies are Amgen's Repatha (evolocumab) and Sanofi/Regeneron's Praluent (alirocumab), ...

The patients came in with high cholesterol. And it was the kind that clings stubbornly to arteries and shadows families for ...

Specifically, the team has designed a strategy to inhibit the expression of PCSK9, a protein that plays a decisive role in modulating plasma levels of low-density lipoprotein cholesterol (LDL-C).

A protein called PCSK9 determines how pancreatic cancer cells metastasize to different parts of the body.