Preview the matchup between Manchester United and Tottenham Hotspur with predictions, odds, over/under, betting lines and more.

Tottenham Hotspur takes on Manchester United in Premier League action at Tottenham Hotspur Stadium in London on Saturday, Nov. 8 at 4:30 a.m. PDT. In what has been an underwhelming EPL season for

Tottenham Hotspur and Manchester United played out a dramatic 2-2 draw in north London on Saturday afternoon. Visitors United took the lead in the 32nd minute when Bryan Mbeumo met a cross into the box and headed the ball past goalkeeper Guglielmo Vicario.

Tottenham will host Manchester United in London on Saturday in one of the most awaited clashes of the season. Thomas Frank, Spurs manager, is currently dealing with some injuries that are affecting both team and performances while the visitors are coming from a finally positive month as Ruben Amorim's Manchester United won three and drew one in the last four Premier League matches.

The match will be available to watch through streaming in the United States, but not on TV. Spurs vs Manchester United will be available to watch across TV channels and streaming services in the UK.

Tottenham Hotspur centre-forward Randal Kolo Muani (26) is set for medical exams after being forced off this Saturday’s Premier League clash between the North London side and Manchester United.

Thomas Frank has defended his substitutions after being booed during Tottenham's 2-2 draw with Manchester United on Saturday.