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DNA METHYLATION MECHANISMS
DNA methylation is an epigenetic mechanism that occurs by the addition of a methyl (CH3) group to DNA, thereby often modifying the function of the genes and affecting gene expression. The most widely characterized DNA methylation process is the covalent addition of the methyl group at the 5-carbon of the cytosine ring resulting in 5 ...
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new drugs are being developed that decrease dna methylation and prevent the removal of acetyl groups from histone explain how these drugs could affect gene expression to help kill tumor cell 24426
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Epigenetics is the study of changes in gene expression or cellular phenotype that do not involve alterations to the underlying DNA sequence. Essentially, it involves modifications that affect how genes are turned on or off without changing the genetic code itself. These changes can be influenced by various factors such as the environment, lifestyle, and experiences, and they can be heritable. Some common mechanisms of epigenetic changes include DNA methylation and histone modification. These pro
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